Search on: SHWARTZMAN REACTION 
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Descriptor English:   Shwartzman Phenomenon 
Descriptor Spanish:   Fenómeno de Shwartzman 
Descriptor Portuguese:   Fenômeno de Shwartzman 
Synonyms English:   Phenomenon, Schwartzman
Phenomenon, Shwartzman
Schwartzman Phenomenon
Schwartzman Reaction
Schwartzman Reactions
Shwartzman Reaction  
Tree Number:   C14.907.454.810
C14.907.940.890
C15.378.463.515.810
Definition English:   Hemorrhagic necrosis that was first demonstrated in rabbits with a two-step reaction, an initial local (intradermal) or general (intravenous) injection of a priming endotoxin (ENDOTOXINS) followed by a second intravenous endotoxin injection (provoking agent) 24 h later. The acute inflammation damages the small blood vessels. The following intravascular coagulation leads to capillary and venous THROMBOSIS and NECROSIS. Shwartzman phenomenon can also occur in other species with a single injection of a provoking agent, and during infections or pregnancy. Its susceptibility depends on the status of IMMUNE SYSTEM, coagulation, FIBRINOLYSIS, and blood flow. 
Allowable Qualifiers English:  
BL blood CF cerebrospinal fluid
CI chemically induced CL classification
CO complications CN congenital
DI diagnosis DG diagnostic imaging
DH diet therapy DT drug therapy
EC economics EM embryology
EN enzymology EP epidemiology
EH ethnology ET etiology
GE genetics HI history
IM immunology ME metabolism
MI microbiology MO mortality
NU nursing PS parasitology
PA pathology PP physiopathology
PC prevention & control PX psychology
RT radiotherapy RH rehabilitation
SU surgery TH therapy
UR urine VE veterinary
VI virology  
Record Number:   13171 
Unique Identifier:   D012790 

Occurrence in VHL:
 

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